A randomized clinical trial to determine the efficacy of manufacturers’ recommended doses of omega-3 fatty acids from different sources in facilitating cardiovascular disease risk reduction

2014

A randomized clinical trial to determine the efficacy of manufacturers’ recommended doses of omega-3 fatty acids from different sources in facilitating cardiovascular disease risk reduction

Ingredient: Fish Oil,Omega-3

Indication: Cardiovascular disease risk

Trial Type: Clinical Trial

Sponsor: Nutrasource

Journal: Lipids in Health and Disease

Authors: Maggie Laidlaw, Carla Cockerline, William Rowe

A Randomized Double-Blind Evaluation of a Novel Biotin and Silicon Ingredient Complex on the Hair and Skin of Healthy Women

2021

A Randomized Double-Blind Evaluation of a Novel Biotin and Silicon Ingredient Complex on the Hair and Skin of Healthy Women

Ingredient: Biotin,Silicon

Indication: Hair and skin health

Trial Type: Clinical Trial

Sponsor: JDS

Journal: Journal of Clinical Experimental Dermatology Research

Authors: Douglas Kalman, Susan Hewlings

A Randomized Double-Blind Evaluation of the Gastrointestinal, Body Composition, Stress Response and Cognitive Function Impacts of Creatine Supplementation in Healthy Adults

2021

A Randomized Double-Blind Evaluation of the Gastrointestinal, Body Composition, Stress Response and Cognitive Function Impacts of Creatine Supplementation in Healthy Adults

Ingredient: Creatine

Indication: Gastrointestinal function, Body Composition, Stress Response, Cognitive Function

Trial Type: Clinical Trial

Sponsor: Glanbia

Journal: EC Nutrition

Authors: Douglas Kalman

A Randomized Double-Blind Placebo-Controlled Trial of a Purported Dietary Supplement Cognitive Enhancer in Healthy Teenage Subjects

2022

A Randomized Double-Blind Placebo-Controlled Trial of a Purported Dietary Supplement Cognitive Enhancer in Healthy Teenage Subjects

Ingredient: Alpha-GPC,Phosphatidylserine,Pyrroloquinoline quinone (PQQ),Spearmint

Indication: Cognitive function

Trial Type: Clinical Trial

Sponsor: HK Pros

Journal: Journal of Exercise and Nutrition

Authors: Lois Lin, Ashley LeMoire

A Randomized, Double-Blind, Clinical Trial of the Effects of VitaBeard® on Facial Hair Growth in Healthy Adult Men

2019

A Randomized, Double-Blind, Clinical Trial of the Effects of VitaBeard® on Facial Hair Growth in Healthy Adult Men

Ingredient: Multivitamins

Indication: Hair growth

Trial Type: Clinical Trial

Sponsor: EC Nutrition

Journal: Cureus

Authors: Joshua Baisley, Anna De Boer

A Randomized, Double-Blind, Placebo-Controlled, Comparator Trial Evaluating Magtein® Magnesium Supplement on Quality of Life as Related to Levels of Stress, Anxiety, Fear and Other Indicators

2022

A Randomized, Double-Blind, Placebo-Controlled, Comparator Trial Evaluating Magtein® Magnesium Supplement on Quality of Life as Related to Levels of Stress, Anxiety, Fear and Other Indicators

Ingredient: Magnesium L-threonate

Indication: Stress, Anxiety

Trial Type: Clinical Trial

Sponsor: AIDP

Journal: EC Nutrition

Authors: Susan Hewlings, Douglas Kalman

A Randomized, Placebo-Controlled, Double-Blind Crossover Study to Assess a Unique Phytosterol Ester Formulation in Lowering LDL Cholesterol Utilizing a Novel Virtual Tracking Tool

2019

A Randomized, Placebo-Controlled, Double-Blind Crossover Study to Assess a Unique Phytosterol Ester Formulation in Lowering LDL Cholesterol Utilizing a Novel Virtual Tracking Tool

Ingredient: Phytosterol

Indication: Blood lipids, LDL

Trial Type: Clinical Trial

Sponsor: BASF SE, Segterra

Journal: Nutrients

Authors: Susan Hewlings

An Evaluation of the Effects of a Non-caffeinated Energy Dietary Supplement on Cognitive and Physical Performance: A Randomized Double-Blind Placebo-Controlled Study

2021

An Evaluation of the Effects of a Non-caffeinated Energy Dietary Supplement on Cognitive and Physical Performance: A Randomized Double-Blind Placebo-Controlled Study

Ingredient: Bacopa monnieri bacosides,Kaempferia parviflora methoxy flavones,Moringa oleifera leaf saponins,Pomegranate peel polyphenols

Indication: Cognitive Function, Physical Performance

Trial Type: Clinical Trial

Sponsor: Glanbia

Journal: Cureus

Authors: Douglas Kalman, Susan Hewlings

Bacillus coagulans Unique IS2 Improves Stool Characteristics in Healthy Adults with Infrequent Bowel Movements: A Randomized, Double-Blind, Placebo-Controlled Trial

2025

Bacillus coagulans Unique IS2 Improves Stool Characteristics in Healthy Adults with Infrequent Bowel Movements: A Randomized, Double-Blind, Placebo-Controlled Trial

Ingredient: Bacillus coagulans Unique IS2,Probiotics

Indication: Stool Characteristics, Bowel Movements, Gut Health

Trial Type: Clinical Trial

Sponsor: PepsiCo

Journal: Beneficial Microbes

Authors: Ashley LeMoire, Lois Lin, Adam Kuttenkeuler, Joshua Baisley, Jun Wang, Stephanie-Anne Girard, Stephanie Recker, Anthony Bier

Coconuts and Health: Different Chain Lengths of Saturated Fats Require Different Consideration

2020

Coconuts and Health: Different Chain Lengths of Saturated Fats Require Different Consideration

Ingredient: Coconut

Indication: General Health

Trial Type: Review and Meta-analysis

Journal: Journal of Cardiovascular Development and Disease

Authors: Susan Hewlings

Comparative membrane incorporation of omega-3 fish oil triglyceride preparations differing by degree of re-esterification: A sixteen-week randomized intervention trial

2023

Comparative membrane incorporation of omega-3 fish oil triglyceride preparations differing by degree of re-esterification: A sixteen-week randomized intervention trial

Ingredient: Fish Oil,Omega-3

Indication: Bioavailability, Blood Lipids

Trial Type: Clinical Trial

Sponsor: Nordic Naturals

Journal: PLOS One

Authors: Maggie Laidlaw

Consumption of Solnul™ Resistant Potato Starch Produces a Prebiotic Effect in a Randomized, Placebo-Controlled Clinical Trial

2023

Consumption of Solnul™ Resistant Potato Starch Produces a Prebiotic Effect in a Randomized, Placebo-Controlled Clinical Trial

Ingredient: Prebiotics

Indication: Gut Health

Trial Type: Clinical Trial

Sponsor: Solnul

Journal: Nutrients

Authors: Joshua Baisley

Correlation of omega-3 levels in serum phospholipid from 2053 human blood samples with key fatty acid ratios

2009

Correlation of omega-3 levels in serum phospholipid from 2053 human blood samples with key fatty acid ratios

Ingredient: Fish Oil,Omega-3

Indication: Cardiovascular Disease Risk

Trial Type: Toxicology

Sponsor: Nutrasource

Journal: Nutrition Journal

Authors: William Rowe

Development of a Standardized Clinical Protocol for Ranking Foods and Meals Based on Postprandial Triglyceride Responses: The Lipemic Index

2011

Development of a Standardized Clinical Protocol for Ranking Foods and Meals Based on Postprandial Triglyceride Responses: The Lipemic Index

Ingredient: Fat Based Functional Beverage

Indication: Cardiovascular Disease Risk

Trial Type: Methodology

Sponsor: Nutrasource

Journal: ISRN Vascular Medicine

Authors: Erin O'Reilly, Maggie Laidlaw

Eating Disorders and Dietary Supplements: A Review of the Science

2023

Eating Disorders and Dietary Supplements: A Review of the Science

Ingredient: Dietary supplements

Indication: Eating disorders

Trial Type: Reviews and Meta-analysis

Journal: Nutrients

Authors: Susan Hewlings

Effect of Bacillus subtilis ATCC 122264 on Intestinal Gas Symptoms and Quality of Life in Adults with Functional Bloating

2025

Effect of Bacillus subtilis ATCC 122264 on Intestinal Gas Symptoms and Quality of Life in Adults with Functional Bloating

Ingredient: Bacillus subtilis ATCC 122264,Probiotics

Indication: Intestinal Gas

Trial Type: Clinical Trial

Sponsor: Kerry

Journal: Beneficial Microbes

Authors: Ashley LeMoire, Lois Lin, Stephanie-Anne Girard, Joshua Baisley, Jun Wang, Ambreen Atif

Effects of Limosilactobacillus reuteri strains PTA-126787 and PTA-126788 on intestinal barrier integrity and immune homeostasis in an alcohol-induced leaky gut model

2024

Effects of Limosilactobacillus reuteri strains PTA-126787 and PTA-126788 on intestinal barrier integrity and immune homeostasis in an alcohol-induced leaky gut model

Ingredient: Limosilactobacillus reuteri strain PTA-126787,Limosilactobacillus reuteri strain PTA-126788

Indication: Intestinal Barrier Integrity

Trial Type: Toxicology

Sponsor: BiomEdit

Journal: Scientific Reports

Authors: Laurie Dolan

Efficacy of a unique omega-3 formulation on the correction of nutritional deficiency and its effects on cardiovascular disease risk factors in a randomized controlled VASCAZEN® REVEAL Trial

2014

Efficacy of a unique omega-3 formulation on the correction of nutritional deficiency and its effects on cardiovascular disease risk factors in a randomized controlled VASCAZEN® REVEAL Trial

Ingredient: Fish Oil,Omega-3

Indication: Nutritional deficiency, cardiovascular disease risk

Trial Type: Clinical Trial

Sponsor: Pivotal Therapeutics

Journal: Molecular and Cellular Biochemistry

Authors: William Rowe, Maggie Laidlaw, Carla Cockerline

Examination of marine and vegetable oil oxidation data from a multi-year, third-party database

2018

Examination of marine and vegetable oil oxidation data from a multi-year, third-party database

Ingredient: Fish Oil

Trial Type: Toxicology

Sponsor: GOED

Journal: Food Chemistry

Authors: Anna De Boer, Kevin Yan, William Rowe

Genotoxicity evaluation of magnesium salts of isobutyrate and 2-methylbutyrate

2021

Genotoxicity evaluation of magnesium salts of isobutyrate and 2-methylbutyrate

Ingredient: Magnesium salts

Indication: Preclinical genotoxicity

Trial Type: Toxicology

Sponsor: Zinpro Animal Nutrition

Journal: Toxicol Rep

Authors: Laurie Dolan

Lowering plasma S-adenosylhomocysteine (SAH) in healthy adults with elevated SAH and normal homocysteine using nutritional supplementation

2025

Lowering plasma S-adenosylhomocysteine (SAH) in healthy adults with elevated SAH and normal homocysteine using nutritional supplementation

Ingredient: Alpha-GPC,Ashwagandha,Creatine

Indication: S-Adenosylhomocysteine, Cellular Methylation

Trial Type: Clinical Trial

Sponsor: Standard Process

Journal: Nutrition Metabolism Cardiovascular Diseases

Authors: Jaustin Dufour, Lois Lin, Jun Wang, Bisma Sharif

Nicotinamide riboside and pterostilbene reduces markers of hepatic inflammation in NAFLD: A double‐blind, placebo‐controlled clinical trial

2023

Nicotinamide riboside and pterostilbene reduces markers of hepatic inflammation in NAFLD: A double‐blind, placebo‐controlled clinical trial

Ingredient: Nicotinamide Riboside,Pterostilbene

Indication: Hepatic inflammation in NAFLD

Trial Type: Clinical Trial

Sponsor: Elysium

Journal: Hepatology

Authors: Rodney Butt

Omega-3 Long-Chain Polyunsaturated Fatty Acid Content and Oxidation State of Fish Oil Supplements in New Zealand

2017

Omega-3 Long-Chain Polyunsaturated Fatty Acid Content and Oxidation State of Fish Oil Supplements in New Zealand

Ingredient: Fish Oil,Omega-3

Trial Type: Toxicology

Sponsor: GOED

Journal: Scientific Reports

Authors: Kevin Yan

Palm Fruit Bioactive Complex (PFBc), a Source of Polyphenols, Demonstrates Potential Benefits for Inflammaging and Related Cognitive Function

2021

Palm Fruit Bioactive Complex (PFBc), a Source of Polyphenols, Demonstrates Potential Benefits for Inflammaging and Related Cognitive Function

Ingredient: Palm Fruit

Indication: Inflammation, Aging, Cognitive Function

Trial Type: Review and Meta-analysis

Sponsor: Phenolaeis

Journal: Nutrients

Authors: Susan Hewlings, Douglas Kalman

Pharmacokinetic Evaluation of a Single 5-Gram Bolus of Creatine Monohydrate Versus Two Other Creatine-Containing Investigational Products

2022

Pharmacokinetic Evaluation of a Single 5-Gram Bolus of Creatine Monohydrate Versus Two Other Creatine-Containing Investigational Products

Ingredient: Creatine

Indication: Exercise

Trial Type: Clinical Trial

Sponsor: Glanbia

Journal: Cureus

Authors: Joshua Baisley, Douglas Kalman

Physical, Psychological, and Biochemical Effects of Palm Fruit Bioactive complex (PFBc) (Elaeis guineensis)

2020

Physical, Psychological, and Biochemical Effects of Palm Fruit Bioactive complex (PFBc) (Elaeis guineensis)

Ingredient: Palm Fruit

Indication: Body Composition, Mood State, Cellular Damage, Gut Microbiome, Oxidative Stress

Trial Type: Clinical Trial

Sponsor: Phenolaeis

Journal: EC Nutrition

Authors: Susan Hewlings, Douglas Kalman

Possible in vitro Artefacts Associated with the Collection and Processing of Blood for Omega-3 Fatty Acid Analysis

2015

Possible in vitro Artefacts Associated with the Collection and Processing of Blood for Omega-3 Fatty Acid Analysis

Ingredient: Fish Oil,Omega-3

Indication: Blood processing, Omega-3

Trial Type: Toxicology

Sponsor: IRAP

Journal: The FASEB (Federation of American Societies for Experimental Biology) Journal

Authors: Erin O'Reilly, Maggie Laidlaw, Rodney Butt, Katie Keene

Resistant potato starch supplementation reduces serum histamine levels in healthy adults with links to attenuated intestinal permeability

2023

Resistant potato starch supplementation reduces serum histamine levels in healthy adults with links to attenuated intestinal permeability

Ingredient: Prebiotics

Indication: Gut Health

Trial Type: Clinical Trial

Sponsor: Solnul

Journal: Journal of Functional Foods

Authors: Joshua Baisley

Revisiting the Concepts of Prebiotic and Prebiotic Effect in Light of Scientific and Regulatory Progress—A Consensus Paper From the Global Prebiotic Association

2024

Revisiting the Concepts of Prebiotic and Prebiotic Effect in Light of Scientific and Regulatory Progress—A Consensus Paper From the Global Prebiotic Association

Ingredient: Bacillus coagulans Unique IS2,Prebiotics

Trial Type: Reviews and Meta-analysis

Sponsor: GPA

Journal: Advances in Nutrition

Authors: Santa Antwan, Paula Guerra, Tania John

Safety of a Sustainably Produced, Bioengineered, Nature-Identical Salidroside Compound

2022

Safety of a Sustainably Produced, Bioengineered, Nature-Identical Salidroside Compound

Ingredient: Salidroside

Indication: Safety, Preclinical Toxicology (genotoxicity, in vivo toxicity)

Trial Type: Toxicology

Sponsor: DoubleRainbow Biosciences Inc.

Journal: Nutrients

Authors: Amy Mozingo, Kaiti Valm, Margitta Dziwenka

Safety of Elixinol Hemp Extract: In Vitro Genetic Toxicity and Subchronic Toxicity in Rats

2023

Safety of Elixinol Hemp Extract: In Vitro Genetic Toxicity and Subchronic Toxicity in Rats

Ingredient: Hemp oil

Indication: Preclinical toxicology

Trial Type: Toxicology

Sponsor: Elixinol

Journal: Journal of Toxicology

Authors: Margitta Dziwenka, Laurie Dolan

Safety Study of Cannabidiol Products in Healthy Dogs

2024

Safety Study of Cannabidiol Products in Healthy Dogs

Ingredient: CBD

Indication: Toxicology

Trial Type: Preclinical Studies

Sponsor: National Animal Supplement Council (NASC)

Journal: Frontiers in Veterinary Science

Authors: Margitta Dziwenka, Kaiti Valm, Jennifer Kovacs-Nolan

Subchronic Oral Toxicity Assessment of Bacillus velezensis Strain BV379 in Sprague-Dawley Rats

2024

Subchronic Oral Toxicity Assessment of Bacillus velezensis Strain BV379 in Sprague-Dawley Rats

Ingredient: Probiotics

Indication: Toxicology

Trial Type: Toxicology

Sponsor: BIO-CAT

Journal: Human & Experimental Toxicology

Authors: Laurie Dolan

The Safety of Multiple-Dose Liquid Blend Containing Kava and Kratom in Healthy Adults

2024

The Safety of Multiple-Dose Liquid Blend Containing Kava and Kratom in Healthy Adults

Ingredient: Kava,Kratom

Indication: Safety

Trial Type: Clinical Trial

Sponsor: Botanic Tonics

Journal: Cureus

Authors: Jaustin Dufour, Lois Lin, Jun Wang, Joshua Baisley, Ambreen Atif

Toxicity Investigations of (R)-3-Hydroxybutyrate Glycerides In Vitro and in Male and Female Rats

2022

Toxicity Investigations of (R)-3-Hydroxybutyrate Glycerides In Vitro and in Male and Female Rats

Ingredient: (R)-3-Hydroxybutyrate Glycerides

Indication: Toxicology

Trial Type: Toxicology

Sponsor: Tecton

Journal: Nutrients

Authors: Laurie Dolan, Benjamin Arceneaux

Toxicological and safety evaluations of Weissella cibaria strain CMU in animal toxicity and genotoxicity

2022

Toxicological and safety evaluations of Weissella cibaria strain CMU in animal toxicity and genotoxicity

Ingredient: Probiotics,Weissella cibaria strain CMU

Indication: Preclinical toxicity, Genotoxicity

Trial Type: Toxicology

Sponsor: OraPharm

Journal: Toxicological Research

Authors: Laurie Dolan, Benjamin Arceneaux

Toxicological safety assessment of HempChoice® hemp oil extract; a proprietary extract consisting of a high concentration of cannabidiol (CBD) in addition to other phytocannabinoids and terpenes derived from CannabissativaL

2023

Toxicological safety assessment of HempChoice® hemp oil extract; a proprietary extract consisting of a high concentration of cannabidiol (CBD) in addition to other phytocannabinoids and terpenes derived from CannabissativaL

Ingredient: CBD,Hemp oil

Indication: Preclinical Toxicology

Trial Type: Toxicology

Sponsor: Geocann

Journal: Heliyon

Authors: Margitta Dziwenka

Toxicological safety of VOHO Hemp Oil; a supercritical fluid extract from the aerial parts of hemp

2021

Toxicological safety of VOHO Hemp Oil; a supercritical fluid extract from the aerial parts of hemp

Ingredient: Hemp oil

Indication: Preclinical Toxicology

Trial Type: Toxicology

Sponsor: HempFusion

Journal: PLOS One

Authors: Margitta Dziwenka, Laurie Dolan

Transgenic Canola Oil Improved Blood Omega-3 Profiles: A Randomized, Placebo-Controlled Trial in Healthy Adults

2022

Transgenic Canola Oil Improved Blood Omega-3 Profiles: A Randomized, Placebo-Controlled Trial in Healthy Adults

Ingredient: Fish Oil,Omega-3,Transgenic canola oil

Indication: Bioavailability

Trial Type: Clinical Trial

Sponsor: Nuseed

Journal: Frontiers in Nutrition

Authors: Lois Lin, Joshua Baisley, Anthony Bier, Drasty Vora